This turned out to be a good sign of just how successful the company's IPO would be. The institutional investor bought 8.7 million shares of the stock in a transaction took place on 6/30/2020. Guardant Health held its initial public offering (IPO) in October 2018. Returns as of 12/15/2020. The stock market plunged as the novel coronavirus and the disease that it causes, COVID-19, spread across the world. Investment Thesis. An even greater opportunity for Guardant Health, though, lies with its LUNAR liquid biopsies, which are currently available for research use only. A subsequent respite in the virus spread will likely accelerate the recovery in test volumes as patients eventually return to doctors’ offices to seek cancer care, something they cannot postpone indefinitely. One of the most important of these was the decision by Palmetto GBA to make Guardant360 the first (and, so far, only) liquid biopsy to receive broad coverage for use in most types of advanced solid tumors. Both tests feed the development of the company’s LUNAR program. 0. Guardant Health thinks that its Guardant360 liquid biopsy has a $6 billion addressable annual market in the U.S. alone. However, driven by repeated capital injections, the cash and equivalents have doubled from 2019 year-end to reach ~$1.0 billion in Q3 2020. So how much would that $10,000 investment in the company's IPO be worth now? If Guardant Health can capture a significant share of these markets, its long-term returns could make the 360% gain since its IPO look like chump change. Meanwhile, thanks to advances in genomics, precision-driven cancer treatments are gaining momentum. 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The NTM EV/Sales is also trading at a discount compared to historicals. Great Protection In An Uncertain Environment: Guardant Health Inc. (GH) and... Edward Bosworth-November 7, 2020. Anna has 6 jobs listed on their profile. See you at the top! Indicating ~32.9% YoY growth, ~$284.9 million of consensus revenue forecast for 2020 implies ~21.6% YoY growth for Q4 2020. As investors, we're taught one simple truth: Nothing is guaranteed. The potential U.S. market for LUNAR-1 is around $15 billion. Disclosure: I/we have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours. Backed by better payer coverage for its late-stage cancer detection test, Guardant Health, Inc. has seen its top-line rising more than a two-fold from the previous year. Guardant Health (NASDAQ:GH) definitely has such an X factor. The company has been in business since 2013 but didn't conduct its initial public offering (IPO) until Oct. 4, 2018. NVDA. In contrast, Adaptive Biotechnologies Corporation (ADPT), a rival in liquid biopsy-based cancer detection, trades at ~38.8x in terms of NTM EV/Sales with only a ~9.6% discount to its 2019 average. The Ascent is The Motley Fool's new personal finance brand devoted to helping you live a richer life. A look at the technology behind Guardant's diagnostics system, and some speculation as to which companies might be a potential suitor in a buyout According to Illumina, early detection could make up ~61% of the global market for cancer genetic sequencing, which is growing at 27% of CAGR (compound annual growth rate) to reach $75 billion by 2035. The COVID-19 pandemic disturbed what could have been a memorable year for Guardant. Guardant Health: FDA Signoff And Vaccine Optimism To Materialize Gains. Investors scoop up shares because of a fear of missing out. This study pitted Guardant Health's liquid biopsy against standard-of-care tissue testing in detecting key biomarkers in patients with advanced non-small-cell lung cancer (NSCLC). Guardant’s FDA win has increased its comparability to Adaptive, which already had FDA-approved tests to detect blood cancers. With EV at 28.5x of 12-month forward sales, the company trades at a ~24.8% discount to its 2019 average of ~37.9x. In August, the FDA greenlighted its liquid biopsy test, Guardant360 CDx, for tumor mutation profiling of solid tumors and as a companion diagnostic to identify non-small cell lung cancer (NSCLC) patients suitable for Tagrisso® (osimertinib). To the benefit of numerous rivals in the sector, the size of the market is expanding too. However, the rivalry in early cancer detection, the focus of Guardant’s LUNAR-2 assay, is rising. On an LTM (last twelve-month) basis, the company’s top-line had more than doubled compared to the year-ago period for four consecutive quarters through Q1 2020 (first quarter of 2020). Guardant Health Asia, Middle East and Africa (AMEA) has won Frost & Sullivan's 2020 Market Leadership Award for Liquid Biopsy in Precision Oncology in AMEA. In September, Illumina, Inc. (ILMN) paid $7.1 billion in cash and stock to acquire GRAIL, Inc. (GRAL), a developer of liquid biopsy-based tests for early detection. With the FDA approval for Guardant360, Guardant Health, Inc. has achieved a milestone for its broad array of cancer detection tests. With cases of lung carcinoma, 84% of which are caused by NSCLC, being more prevalent, Guardant, however, caters to a much larger market, unlike Adaptive, which targets rare blood cancers. I have no business relationship with any company whose stock is mentioned in this article. Better Coronavirus Stock: Quidel or Guardant Health? The test volumes from biopharma customers, generating ~37.1% of the top-line, will expand at a similar rate to the past quarter. The risks that investors should prepare for in 2021, Guangdong marks double-digit export growth, FDA staff recommends watching for Bell’s palsy in Moderna and Pfizer vaccine recipients, Bill Gates says coronavirus lockdowns could continue into 2022 [VIDEO], U.S. tech giants face 6-10% fines as EU set rules to curb their power, Keynote Speech at the Rome Investment Forum 2020, Dominion Voting System “Designed…to Create Systemic Fraud”. At that point, an initial investment of $10,000 in Guardant Health's IPO would have been worth $46,714. When they arrive on the scene, investors flock to them. Cumulative Growth of a $10,000 Investment in Stock Advisor Calculated by Time-Weighted Return. As the company’s long-term prospects in early cancer detection and the precision-oncology outweigh the near-term risks from COVID-19, Guardant is a compelling ‘Buy’ for us. Roche (SIX:ROG; OTCQB:RHHBY), Basel, Switzerland. Janssen Biotech has already teamed up with Guardant to develop and commercialize Guardant360 as a companion diagnostic for its experimental NSCLC therapy, amivantamab. Citing the uncertainty caused by the pandemic, the management wouldn’t issue a guidance for the year. The most promising test, under development seeking FDA approval and CMS coverage, the LUNAR-2 assay targets early cancer detection in asymptomatic and high-risk individuals. Facebook. Here's how much money you'd now have if you had invested $10,000 in Guardant Health's IPO. Let's conquer your financial goals together...faster. Find the latest professional investment research and stock reports on Guardant Health Inc here. Keith began writing for the Fool in 2012 and focuses primarily on healthcare investing topics. However, it doesn’t have repeat customers like Guardant Health where patients need to get retested every so often. If you enjoyed this article and wish to receive updates on my latest research, click “Follow” next to my name at the top. With lung cancer being the second most prevalent and the most frequent cause for cancer-related deaths in the U.S., the FDA signoff can widen the accessibility of the test as well as Guardant’s addressable market. But margin expansion hasn’t offset the impact from shrinking revenue growth, and for the second quarter in a row, the operating loss has widened by multiple times from a year ago. Nearly $36,250. That's still a fantastic performance even with the recent coronavirus-fueled decline. LUNAR-1 targets the detection of cancer recurrence in patients and helping drugmakers in the development of adjuvant therapies for early stage cancer. Companies . WhatsApp. Investment Thesis. It's usually because there's a perception that the companies are on to something big. Thrive Earlier Detection Corp., Cambridge, Mass. Edward Bosworth - September 3, 2020. The regulatory signoff should raise hopes for Guardant’s broad portfolio of cancer tests, which aim to detect all stages of the disease through liquid biopsy. Certain stocks have an X factor. Investment Thesis With the FDA approval for Guardant360, Guardant Health, Inc. (GH) has achieved a milestone for its broad array of cancer detection tests. I’m convinced that Guardant Health can deliver mind-blowing returns over the next 10 years as well. Via SeekingAlpha.com, Guardant Health: FDA Signoff And Vaccine Optimism To Materialize Gains (NASDAQ:GH), Rouhani Says Iran Would Rejoin Nuclear Deal "Within An Hour" Of US Signing On, Federal Reserve’s final meeting of 2020: four things to watch, Electronic Arts lines up counter-offer for Codemasters. I/we have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours. Gets Its Catalyst And Trades Up: Twitter Inc. (TWTR), Guardant Health Inc. (GH) By. 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